And that chick from Twilight who got nominated for an Oscar but wasn't good enough to play Bella Swan.
Worked out well for her in the end though, didn't?
This looks like its going to be a tearjerker kind of movie, but then again, Seth Rogen is HIGHlarious, so maybe it won't be so sad. Then again, is cancer ever really funny. We don't know. We just love us some Joseph Gordon-Levitt, so if he's in it, we're seeing it!
Check out this newly released trailer for 50/50 in the video (above).