Home Videos Photos Shop
PerezHilton CocoPerez Khloé Selena G. Meghan Markle T. Swift PerezTV

Angelina Jolie's Gene Mutation And Surgery: Everything You Need To Know!

| Filed under: Angelina JolieHealthCancer

important facts about angelina jolie gene mutation and surgery

Angelina Jolie has been the center of attention the last couple of days for raising awareness for women's health issues when she announced she was having preventative surgeries!

But some people are still a little unclear about all of the medical jargon that has come along with the news, so here are some important facts to help clear up any lingering confusion:

What is a BRCA1 gene?

Angelina said she was at high risk of breast and ovarian cancer due to a faulty BRCA1 gene, but not everyone knows exactly what that is. BRCA1 is a gene that everyone has and is responsible for repairing damaged DNA, but a mutation of the gene can cause it to produce protein that greatly increases the risks of cancer.

Is it common to have a BRCA1 mutation?

Not at all. Less than 1 percent of the U.S. population has a BRCA1 mutation.

Can a faulty BRCA1 gene be passed down to my children?

Unfortunately, yes. Children can inherit a mutated BRCA1 gene from either their mother OR their father, so if there is a history of cancer or faulty genes in your family it is HIGHLY recommended that you get tested.

How high are my chances of getting breast or ovarian cancer if I have a BRCA1 mutation?

Only about 5% of all 220,000 cancer patients are caused by the gene mutation, but your chances are still significantly higher than someone who doesn't have a faulty gene. People with a BRCA1 mutation have a 60-85% chance of developing breast cancer and a 20-50% chance of developing ovarian cancer.

How do I get tested for it?

Getting tested for a gene mutation is usually just a simple blood or saliva test, but it's important to keep in mind that some insurance companies wont cover the cost because it might be considered "high-risk," so an analysis could cost around $3,000.

What should I do if I have a faulty gene?

Angelina probably went about it the best way possible. Many women will choose to have mastectomies or closely monitor themselves for warning signs if they have a BRCA1 mutation. Doctors also recommend women get their ovaries and fallopian tubes removed before the age of 40, ESPECIALLY if they are done having children. However, these procedures could end up leading to early menopause in some women.

Hopefully this helps answer any questions or concerns people have about the risks of getting cancer, but of course if you still have any major questions we HIGHLY recommend scheduling a checkup with your doctor!

After all, they're the experts! LOLz!

[Image via Adriana M. Barraza/WENN.]

Tags: , , , , , , , , , , ,

Celebrities Who've Opened Up About Miscarriage
Celebs With Secret Talents!
The MOST Shocking Celebrity Pregnancies!
Critics' Choice Awards 2018: ALL The Red Carpet Looks!
Epic Side-Eye Hall Of Fame!
Golden Globes 2018: ALL The Red Carpet Pics!

4 comments to “Angelina Jolie's Gene Mutation And Surgery: Everything You Need To Know!”

  1. 1

    I think it is totally cool that you are educating people about her surgeries. This was brave on her part and I applaud her letting the world know.

  2. cathy says – reply to this


    Perez ,only 20 to 30% of women with this Gene which in not many, choose to take the Drastic measure of having a Double Mastectomy.Angelina panicked out of the fear of what happened to her Mother.The Dr's should have advised her to take more time in making her decision. As reported by you Angelinas breast tissue came back 100% benign.

  3. Mary says – reply to this


    I think saying that "she went about it the best way possible" is too strong of a statement. We also need to think of women who have the gene and choose not to go through surgery. They too are heroes and strong women. The choice is up to each woman and the choice each woman makes is the best way possible for them. This is a hot topic I love that it is raising awareness…but we should all be sensitive to both sides and different decisions. It is a lot of money to spend. As you stated most insurances don't pay for the test which means most won't pay for the surgery if it is elective. Love to Angie for makeing her decision!! But also much love to the other ladies out there that made a different choice!!! ;-) love you Perez!!!

  4. Michelle says – reply to this


    This is all a PR scam to promote the test to make much dollars for for-profit companies. Ladies, keep your tatas! Don't cut them out only to have them replaced by synthetic materials out of fear. Stay natural–stay your beautiful born self!