But they totally are and we absolutely love it!!
The famous ladies are teaming up to bring the laughs in their new comedy film Hot Pursuit!
The film is about Reese playing a bumbling cop who has to protect Sofia, the wife of a drug cartel boss.
They each play their role perfectly in the trailer, Reese's doofy cop balanced by Sofia's fiery latina. There just might be some real comedic chemistry there.
The movie comes out in theaters on May 8th, so until then just watch the trailer on loop and get all hot and bothered!
Check out the video (below) and prepare to get your laugh on!