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Headline Of The Week Weak
Filed under: Headline of the Week
"Did a Bone Marrow Transplant Cure a Cancer Patient of AIDS?"
Really???? CLICK HERE to read the article accompanying this headline.
Did a Bone Marrow Transplant Cure a Cancer Patient of AIDS?
A 42-year-old man who had both leukemia and AIDS received a bone marrow transplant — a common, late-stage treatment for that type of cancer. His doctor selected a bone marrow donor who had a rare genetic mutation that renders people virtually immune to HIV. The transplant appeared to cure the patient of AIDS.
We’re as wary as the next guy of inferring too much from a single case study. Maybe it was a fluke; maybe there were unknown factors at work. But this one is pretty intriguing.
The case was presented at a conference earlier this year (here’s the abstract), and written up in this morning’s WSJ.
As is common for bone marrow transplant recipients, the patient first had radiation and chemotherapy, which tends to kill off many of the immune cells that harbor HIV. After the transplant, the patient’s immune system was repopulated by cells created by the donor marrow.
The donor had a mutation, present in about 1% of Europeans, that creates immune system cells that lack a receptor molecule called CCR5. That receptor plays an important role in HIV’s ability to enter the cell. (Pfizer’s HIV drug Selzentry works by blocking CCR5.)
So the patient’s immune system was repopulated with immune cells that carried the mutation. And, nearly two years after undergoing the transplant, he shows no signs of having any HIV left in his body — despite the fact that he hasn’t taken any AIDS drugs since before the transplant.
Perhaps the most important caveat is just how risky bone marrow transplantation is: It’s given to cancer patients after other treatments fail, and it kills up to 30% of patients.
But researchers hope to apply the apparent lessons of this case to strategies using gene therapy (which carries its own risks) to try to induce the protective mutation in patients with HIV.
David Baltimore, who won a Nobel Prize for research on tumor viruses, has started a company to use gene therapy to target HIV. He calls this case “a very good sign” and a virtual “proof of principle” for gene-therapy approaches.
… and WHO cares?
good news, now use a rubber
WOW….that is incredible and gives all hiv+ people a little hope….
Still no luck gettin' lab rats to buttfuck huh?
sounds like good news……….why's that week?
wow, thats kool
very intrguing
Re: mamajud – weak
Bush probably has the cure in his pocket
Re: Fire – Probably people with AIDS, smart one.
whoa! a breakthrough?!!
Re: mamajud – Hey mamajud! What's happening?
headline of the weak??
PEREZ IS AGAINST A CURE FOR AIDS!!!
Hope they find a cure. Too many lives have been lost to this tragic epidemic.
i highly doubt it. but who knows. they need to do some more research and this guy should get a screening done to see if it is fully gone.
but as fire said.. who cares…
Re: Fire – wow what an ignoramus, get a brain
Re: Fire –
Listen you ugly Cunt. Lots of people care, this is important. Don't be and asshole your whole life because you your miserable, It's obvious from the bull shit you write. Your embarrassing and another reason why there are so many stupid people in the world. Get a clue. Pig!!!!!!
WELL DONE FOR POSTING PEREZ. THIS SOUNDS VERY PROMISING FOR THE HIV COMMUNITY. I AM INVOLVED IN HIV/AIDS PREVENTION AND EDUCATION AND I'M SURE THE PEOPLE I WORK WITH WILL SEE THIS AS A POSITIVE BREAKTHROUGH DEVELOPMENT. LET THE UNEDUCATED SCUM BAGS POST THEIR NASTY ASS COMMENTS. WHEN KARMA COMES AROUND FOR THEM THEY WILL SOON HUMBLE THEMSELVES.
for the middle america asshole who said who cares
Listen you ugly Cunt. Lots of people care, this is important. Don't be and asshole your whole life because you your miserable, It's obvious from the bull shit you write. Your embarrassing and another reason why there are so many stupid people in the world. Get a clue. Pig!!!!!!
wow that is amazing but not everyone with HIV can have a bone marrow transplant. Hopefully this information will lead to a further understandng of possible treatments and cures.
Re: _Alice_ – HI you!…hi letty girl……..BALS
Re: FAGS SHOULD BE SMOKED! – and you too
Is this Magic Johnson's secret?
now where the fuck is the cure for cancer? i find it hard to believe that they cant find a cure. especially with all the fucking money that gets raised every single year. like wtf
Perez keep your pecker in your pants and out of some guys mouth, then you will not have to worry if this cure is valid.
Fire fuck you! Who cares? Um millions of people in the world care who have HIV/AIDS.
Morning bitches. See me in the next Batman movie. I'm going to torture him into oblivion existence.
WHO cares….it's a pun (as in World Health Organization). IDIOTS!
Another reason to be hopeful.
As a victim…..I CARE!!!!!!
DIRECT INTRAVEINOUS OZONE THERAPY CURES AIDS!!! IT IS ILLEGAL IN THE U.S.A. BECAUSE PHARMACEUTICAL COMPANIES CAN'T MAKE ANY MONEY OFF OF IT!!!
Re: williexwhip –
THAT'S BECAUSE THE CURE IS FIRSTLY EMOTIONAL. CANCER IS CAUSED BY REPRESSED GUILT AND ANGER. DIRECT INTRAVEINOUS OZONE ALSO CURES CANCER. THE DRUG COMPANIES KNOW THIS, BUT THEY ARE ABOUT MONEY, NOT PEOPLE'S LIVES
My mom knew a couple people that had aids. One lived 7 years, the other lived for 24 years. Never know.
Re: harrybalsac – I read several years ago that lab rats, when placed in overcrowded conditions, will "go gay". It didn't specify if they were just giving blow jobs or going bareback.
June Brigham was the first case of a bone-marrow cure, back in 1990. Her identical twin was her donor, and it was done at the City of Hope in Duarte, CA. UNfortunately, her insurance company delayed the procedure to the point that she was too ill to survive long after the surgery. Her system, however, showed NO HIV at the time. Amazing.
i believe that there may be a cure out there, just not available to the general public because its so expensive, i mean, how long has it been since Magic Johnson came out with HIV or AIDS, and he's still alive and kicking, and actually i read somewhere where it said that he was in"remission"., i didn't think that was possible, i wouldn't be surprised if he's cured, but has to keep it underwraps.
cancer will never be cured
Bone Marrow transplants may kill recipients 30% of the time, but full blown AIDS kills 100% of the time. It is worth the risk to investigate further if it will help eradicate this vicious disease. The challenge will not be the research but finding donors. The lives of many cancer patients are already lost because they cannot find a compatible donor, imagine trying to find donors with this gene mutation?
*speechless, I hope they find a cure. For the people that got it by cheating spouses, poor people didn't ask for it, they should get a second chance.
My heart goes out TO THEM!
That's incredible!
I hope this leads to a cure for HIV!
That's pretty awesome!!! Thanks for updating us, Perez!!!!! *hugs*
Re: danetty757 –
Magic Johnson doesn't have full-blown AIDS, just HIV.
His HIV hasn't developed into AIDS because of all the medicine he's taking.
You could potentially have HIV your entire life and never get AIDS.
Re: williexwhip –
Learn some biology, and maybe you'll understand why cancer hasn't been cured yet.
Re: Fire –
All the people who wish you were never born.
Thats awesome. I think its BS when doctors say the body can't fight hiv on its own. Same with diabetes, supposedly an uncurable thing which people cure themselves of every day, when they start eating right and exercising.
yes… why is that weak? stupid ass
Keep in mind that with regular drug treatments, most HIV carriers can live an average life span. Really and truely, a cure isn't what we need. A vaccination is.
Re: Anonymouse – I completely and unequivocally disagree. Drugs whether the HIV cocktails or insulin for Diabetics or Blood Pressure Medication for Cardiac Patients are wonderful and prolong life BUT they have toxic side effects which over time are very debilitating. Although a drug regimen may control a specific disease, any doctor will tell you that drugs undoubtedly have over time deleterious effects other organs, for example, the kidneys, the cardiovascular system, the nervous system, etc. A cure is most definitely necessary in addition to a vaccine!
omg! seriously how people can be unamazed by this is aastonishing. This is GREAT NEWS.
I personally see it as a sign that nature is letting the earth un-over-populate a bit and then letting us get healthy again. but also it can be seen as a way to manufacture a cure! this is INCREDIBLE.
That's great! All those people who have AIDS now have a hope for a cure. And to all the people who are so dense, stupid, uncaring, and complete and total inbred morons, those people who have left the cruel and nasty comments about gay people, may God strike you with a horrible disease so you can possibly get a small look a life with it. I can't believe how nasty people have become. Is it because you are posting on the internet and you can hide behind your monitor? Is it because you live in your mama's basement, and feel hopeless and useless? Or are you glimpse of how nasty people have become? Either way, I feel nothing but pity and shame for you…
Fire: Maybe in 10 - 15 years when you finally become sexually active you will realize just how stupid you were when typing "Who cares". Anybody who is sexually active SHOULD care. Especially folks who, like yourself, have to subscribe to a pay per lay service.
That is AMAZING! We to this day haven't found a care for any virus from the common cold to AIDS. Maybe this is finally it…..
cure*
Thank you Jesus!
Awesome…let's hope they can find a cure for HIV/AIDS and possible Cancer as well…
Re: Fire – well, then why are you reading and posting in a note you don't care about?? people like you piss me off
Re: Prof. Minerva McGonagle – *possibly
I dont know, I think this is great and I think its ridiculous that people still assume the only way you can get HIV/AIDS is from somebody having gay sex. Please…grow up and stop being so goddamn angry, you're the reason Americans hate everyone.
Oh my god!
Such good news!
I wish that they could cure HIV.
And Cancer!
Well but that is a catch: its hard to find a bone marrow compatible with another person. Its like a lotery. Most of the donaters are relative, or something like that. To find a compatible bone marrow randomly is almost impossible. So to cure billions of people that suffers from HIV by using a bone marrow that is only present in 1% of european population, will be impossible. Sadly, but true.
It makes sense to me that it could; my son had leukemia and so we learned a lot about the blood disorders. AIDS, like leukemia, is in the blood cells.AIDS attacks the white-cells(for immunity). a BMT wipes out the entire immune system and all the blood cells; red-cells, platelets, white-cells….it kills off the cancer cells,and then the BM slowly recovers and rebuilds itself…free of the mutation(disease),and since AIDS is concentrated in the white-cells it makes sense a BMT can possibly "cure" it….
Re: WawaLisa – A possibility(this is what we did) umbilical-cord stem cell banking; this saves a newborn's cord blood, which is compatable to ANY person; it is universal. It can be banked up to 10 years and given as a BMT. There is always a "match",and the good of it is, no one has to die for the stem cells to be donated; it's just in the cord(which they "milk" at the baby's birth) which they would throw away for disposal anyway.This new procedure has the capability of potentially saving many lives. Perhaps there could be a "bank" where everyone could donate their newborn's cord blood and have universal access to it?We banked our baby's blood and have it stored for our 10 year old, who is in remission for leukemia, in case, God forbid, he ever relapses and needs a BMT; it's sort of like insurance.
Re: ChiCharones – : I wholly agree with your sentiment and say Thank you, Thank you, Thank you to the Almighty…
Re: guitar man – WTF? cancer is not caused by fucking anger, are you retarded?
In reply to Fires's comment. Peolpe with HIV and AIDS care you dumbass
Re: Fire –
Um, how about everyone in the WORLD with a heart!!!!!
screw you Fire.
30.8 million people would care.
thats how many are infected.
dumb piece of ignorant crap.
That's nice.
this picture, is exactly what I did for a project…
Last semester for communications, my group was talking about safe sex. We had to argue to the class why we think safe sex is the best bet.
I had the incurable stuff. So I focused on AIDS and took a kick ass picture just like this with one of my friends.
honestly, that is really cool.
CCR5 was also believed to be a gene that stopped some people getting the plague way back then.
AIDS is God's punishment on the gay man!